翻訳と辞書 Words near each other ・ Field hockey at the 2002 Asian Games – Women ・ Field Hockey at the 2003 Afro-Asian Games ・ Field hockey at the 2003 All-Africa Games ・ Field hockey at the 2003 Pan American Games ・ Field hockey at the 2004 Summer Olympics ・ Field hockey at the 2004 Summer Olympics – Men's team squads ・ Field hockey at the 2004 Summer Olympics – Men's tournament ・ Field hockey at the 2004 Summer Olympics – Women's team squads ・ Field hockey at the 2004 Summer Olympics – Women's tournament ・ Field Artillery Tractor ・ Field bean ・ Field Brook ・ Field Broughton ・ Field Building (Chicago) ・ Field camera ・ Field cancerization ・ Field capacity ・ Field Card ・ Field Cate ・ Field Cathedral of the Polish Army ・ Field Club ・ Field coil ・ Field Combat ・ Field Commander ・ Field Communications ・ Field corn ・ Field cornet ・ Field cricket ・ Field cycling ・ Field Dalling Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Field cancerization ： ウィキペディア英語版 Field cancerization Field cancerization (also termed field change, field change cancerization, field carcinogenesis, cancer field effect or premalignant field defect) is a biological process in which large areas of cells at a tissue surface or within an organ are affected by a carcinogenic alteration(s). The process arises from exposure to an injurious environment, often over a lengthy period.〔 ==How field cancerization arises== The initial step in field cancerization is associated with various molecular lesions such as acquired genetic mutations and epigenetic changes, occurring over a widespread, multi-focal "field".〔〔〔〔〔〔〔 These initial molecular changes may subsequently progress to cytologically recognizable premalignant foci of dysplasia, and eventually to carcinoma in situ (CIS) or cancer.〔〔 The image of a longitudinally opened colon resection on this page shows an area of a colon resection that likely has a field cancerization or field defect. It has one cancer and four premalignant polyps. Field cancerization can occur in any tissue.〔 Prominent examples of field cancerization include premalignant field defects in head and neck cancer,〔 lung cancer,〔〔 colorectal cancer,〔 Barrett's esophagus,〔〔〔 skin,〔〔〔 breast ducts〔〔 and bladder.〔〔 Field cancerization has implications for cancer surveillance and treatment.〔〔〔〔〔〔 Despite adequate resection and being histologically normal, the remaining locoregional tissue has an increased risk for developing multiple independent cancers, either synchronously or metachronously.〔〔〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Field cancerization」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.